產(chǎn)品編號 yb-8152R
英文名稱 Anti-FAM50A抗體
中文名稱 FAM50A蛋白抗體
別    名 FAM 50A; Family with sequence similarity 50 member A; HXC 26; HXC26; Protein FAM50A; Protein HXC 26; Protein HXC26; Protein XAP 5; Protein XAP5; XAP 5; XAP 5 protein; XAP5; XAP5 protein; 9F; DXS9928E; FA50A_HUMAN.
Anti-FAM50A抗體  
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAM50A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
FAM50A, also known as DXS9928E, HXC26, XAP5 or 9F, is a 339 amino acid nuclear protein that belongs to the FAM50 family. Expressed ubiquitously with highest expression in fetal kidney, liver and brain, as well as adult heart, spleen, skeletal muscle, prostate and small intestine, FAM50A is thought to function as a transcription factor that may bind to DNA. FAM50A contains an SV40 large T antigen nuclear localization signal and a polymorphic CCG repeat region in its 5’-UTR. Defects in the gene encoding FAM50A may be associated with acute lymphoblastic leukemia, suggesting a possible role for FAM50A in carcinogenesis.

Function:
May be a DNA-binding protein or transcriptional factor.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in all tissues examined. Mostly abundant in fetal brain, liver and kidney; in the adult, high levels were also observed in heart, skeletal muscle, spleen, thymus, prostate and small intestine.

Similarity:
Belongs to the FAM50 family.