產(chǎn)品編號(hào) YB-1253R
英文名稱 Anti-AQP3抗體
中文名稱 水通道蛋白-3抗體
別    名 AQP 3; AQP3; Aquaporin 3 (GIL blood group); Aquaporin 3 (Gill blood group); Aquaporin3; Aquaporin-3; GIL; Gill blood group; AQP3_MOUSE.   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
Anti-AQP3抗體體濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse AQP3 C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. [provided by RefSeq, Aug 2011]
通道蛋白（Channel Protein）
AQP 3主要分布于腎臟集合管上皮細(xì)胞基側(cè)質(zhì)膜,除了對(duì)水有通透性外、還可轉(zhuǎn)運(yùn)尿素和甘油等小分子物質(zhì),而尿素在尿液濃縮機(jī)制中有著重要的作用.
有學(xué)者認(rèn)為：AQP-3的陽性率與某些腫瘤分化程度有關(guān)（胃癌、結(jié)腸癌、乳腺癌、前列腺癌、子宮癌、卵巢癌、甲狀腺癌等